Alpha-particle radiobiological experiments using thin CR-39 detectors
نویسندگان
چکیده
منابع مشابه
Alpha-particle radiobiological experiments using thin CR-39 detectors.
The present paper studied the feasibility of applying comet assay to evaluate the DNA damage in individual HeLa cervix cancer cells after alpha-particle irradiation. We prepared thin CR-39 detectors (<20 microm) as cell-culture substrates, with UV irradiation to shorten the track formation time. After irradiation of the HeLa cells by alpha particles, the tracks on the underside of the CR-39 det...
متن کاملSimple preparation of thin CR-39 detectors for alpha-particle radiobiological experiments
Alpha-particle radiobiological experiments involve irradiating cells with alpha particles and require accurate positions where the alpha particles hit the cells. In the present work, we prepared thin CR-39 detectors from commercially available CR-39 SSNTDs with a thickness of 100 lm by etching them in 1 N NaOH/ethanol at 40 C to below 20 lm. The desired final thickness was achieved within 8 h. ...
متن کاملStudies of biocompatibility of chemically etched CR-39 SSNTDs in view of their applications in alpha-particle radiobiological experiments
Alpha-particle radiobiological experiments involve irradiating cells with alpha particles and require thin biocompatible materials which can record alpha-particle traversals as substrates for cell cultures. The biocompatibilities of chemically etched CR-39 solid-state nuclear track detectors (SSNTDs) using aqueous NaOH or NaOH/ehtanol are studied through the abundance and morphology of the cult...
متن کاملAlpha-particle fluence in radiobiological experiments
Two methods were proposed for determining alpha-particle fluence for radiobiological experiments. The first involved calculating the probabilities of hitting the target for alpha particles emitted from a source through Monte Carlo simulations, which when multiplied by the activity of the source gave the fluence at the target. The second relied on the number of chemically etched alpha-particle t...
متن کاملOptical appearance of alpha particle tracks in CR-39 SSNTD
A ray tracing method based on geometrical optics was used to study the tracks from alpha particles with different energies and with an incident angle of 50 . The transmission operation mode of the microscope is simulated. Considering the distribution of light intensities from the tracks, the mean and the 80% percentile gray levels from real experiments are proposed as quantitative variables to ...
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ژورنال
عنوان ژورنال: Radiation Protection Dosimetry
سال: 2006
ISSN: 1742-3406,0144-8420
DOI: 10.1093/rpd/ncl393